Crizotinib is inhibitor of the c-Met kinase and the NPM-ALK. Crizotinib inhibited cell proliferation in ALK-positive ALCL cells (IC50s=30 nM). Crizotinib is useful in treatment of anaplastic large-cell lymphoma.

prudect name : Crizotinib is inhibitor of the c-Met kinase and the NPM-ALK. Crizotinib inhibited cell proliferation in ALK-positive ALCL cells (IC50s=30 nM). Crizotinib is useful in treatment of anaplastic large-cell lymphoma.
Crizotinib (PF-02341066)

Synonyms: PF2341066CAS NO: 877399-52-5Molecular Formula: C₂₁H₂₂Cl₂FN₅OMolecular Weight: 450.34Purity: 98% minSolubility: In DMSOStorage: −20°C

(24R)-24,25-Dihydroxyvitamin D3 References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18509338