Gambogic Acid is a caged xanthone that is derived from Garcinia hanburyi and functions as a strong apoptotic inducer in many types of cancer cells by inhibiting human Bcl-2 family proteins and activating caspases. Gambogic Acid also blocks Kir2.1 channels with EC50 of ¡Ü 100 nM.Gambogic Acid significantly inhibits human umbilical vein endothelial cell (HUVEC) proliferation, migration, invasion, tube formation, and micro-vessel growth at nM concentration.

prudect name : Gambogic Acid is a caged xanthone that is derived from Garcinia hanburyi and functions as a strong apoptotic inducer in many types of cancer cells by inhibiting human Bcl-2 family proteins and activating caspases. Gambogic Acid also blocks Kir2.1 channels with EC50 of ¡Ü 100 nM.Gambogic Acid significantly inhibits human umbilical vein endothelial cell (HUVEC) proliferation, migration, invasion, tube formation, and micro-vessel growth at nM concentration.
Gambogic acid

Synonyms: CAS NO: 2752-65-0Molecular Formula: C₃₈H₄₄O₈Molecular Weight: 628.75Purity: 98% minSolubility: In DMSOStorage: -20°C

AFQ056 References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18516045