Biological Activity: Potent inhibitor of hypoxia inducible factor 1¦Á prolyl hydroxylase-2 (PHD2) (IC50 = 21 nM). Displays over 100-fold selectivity for PHD2 over factor inhibiting HIF-1 (FIH-1) and histone demethylases JMJD2A, JMJD2C, JMJD2E and JMJD3. Cell permeable.

prudect name : Biological Activity:
Potent inhibitor of hypoxia inducible factor 1¦Á prolyl hydroxylase-2 (PHD2) (IC50 = 21 nM). Displays over 100-fold selectivity for PHD2 over factor inhibiting HIF-1 (FIH-1) and histone demethylases JMJD2A, JMJD2C, JMJD2E and JMJD3. Cell permeable.
IOX2

Synonyms: CAS NO: 931398-72-0Molecular Formula: C₁₉H₁₆N₂O₅Molecular Weight: 352.34Purity: 98% minSolubility: In DMSOStorage: −20°C

ITI007 References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18519871