Paritaprevir is an acylsulfonamide inhibitor of the NS3-4A serine protease that shows promising results as a treatment of hepatitis C.

June 21, 2017

prudect name : Paritaprevir is an acylsulfonamide inhibitor of the NS3-4A serine protease that shows promising results as a treatment of hepatitis C.Paritaprevir;ABT-450;ABT 450 Synonyms: CAS NO: 1216941-48-8Molecular Formula: C40H43N7O7SMolecular…

📌

0💬 read more

Pomalidomide inhibits LPS-induced TNF-_alpha_ release with IC50 of 13 nM.

prudect name : Pomalidomide inhibits LPS-induced TNF-_alpha_ release with IC50 of 13 nM.Pomalidomide Synonyms: CAS NO: 19171-19-8Molecular Formula: C13H11N3O4Molecular Weight: 273.24Purity: 98% minSolubility: In DMSOStorage: -20 oC web site: www.medchemexpress.com

📌

0💬 read more

PNU120596 is a potent and selective positive allosteric ¦Á7 neuronal nicotinic acetylcholine receptors modulator with an EC50 of 0.2 ¦ÌM. PNU120596 (PNU 120596, PNU-120596) has no detectable effect on ¦Á4¦Â2, ¦Á3¦Â4 and ¦Á9¦Á10 receptors. Discovered in a high-throughput screen, PNU120596 (PNU 120596, PNU-120596) enhanced agonist-evoked calcium flux mediated by an engineered variant of the human ¦Á7 nAChR. Electrophysiology studies demonstrated that PNU120596 (PNU 120596, PNU-120596) increased peak agonist-evoked currents mediated by wild-type receptors and also proved a pronounced prolongation of the triggered response in the continued presence of agonist.

prudect name : PNU120596 is a potent and selective positive allosteric ¦Á7 neuronal nicotinic acetylcholine receptors modulator with an EC50 of 0.2 ¦ÌM. PNU120596 (PNU 120596, PNU-120596) has no detectable…

📌

0💬 read more

prudect name : PentostatinSynonyms: CAS NO: 53910-25-1Molecular Formula: C11H16N4O4Molecular Weight: 268.27Purity: 98% minSolubility: In DMSOStorage:

prudect name : Pentostatin Synonyms: CAS NO: 53910-25-1Molecular Formula: C11H16N4O4Molecular Weight: 268.27Purity: 98% minSolubility: In DMSOStorage: -20°C web site: www.medchemexpress.com

📌

0💬 read more

Pimobendan is a selective inhibitor of PDE3 with IC50 of 0.32 ¦ÌM.

prudect name : Pimobendan is a selective inhibitor of PDE3 with IC50 of 0.32 ¦ÌM.Pimobendan Synonyms: CAS NO: 74150-27-9Molecular Formula: C19H18N4O2Molecular Weight: 334.37Purity: 98% minSolubility: In DMSOStorage: -20 oC web…

📌

0💬 read more

prudect name : Prostacyclin sodium saltSynonyms: CAS NO: 61849-14-7Molecular Formula: C20H31O5.NaMolecular Weight: 374.45Purity: 99%Solubility: Storage:

prudect name : Prostacyclin sodium salt Synonyms: CAS NO: 61849-14-7Molecular Formula: C20H31O5.NaMolecular Weight: 374.45Purity: 99%Solubility: Storage: -20¡æ web site: www.medchemexpress.com

📌

0💬 read more

PCI-24781 (CRA-024781) is a novel broad spectrum hydroxamic acid-based inhibitor of histone deacetylase (HDAC) that shows antitumor activity in vitro and in vivo preclinically and is under evaluation in phase I clinical trials for cancer.PCI-24781 inhibited pure recombinant HDAC1 with a Ki of 0.007 Mmol/L, and also inhibited the other HDAC isozymes HDAC2, HDAC3/SMRT, HDAC6, HDAC8, and HDAC10 in the nanomolar range.

prudect name : PCI-24781 (CRA-024781) is a novel broad spectrum hydroxamic acid-based inhibitor of histone deacetylase (HDAC) that shows antitumor activity in vitro and in vivo preclinically and is under…

📌

0💬 read more

PJ34 HCl is the hydrochloride salt of PJ34, which is a PARP inhibitor with EC50 of 20 nM and is equally potent to PARP1/2.

prudect name : PJ34 HCl is the hydrochloride salt of PJ34, which is a PARP inhibitor with EC50 of 20 nM and is equally potent to PARP1/2.PJ 34 hydrochloride Synonyms:…

📌

0💬 read more

PIK-294 is a highly selective p110¦Ä inhibitor with IC50 of 10 nM, 1000-, 49- and 16-fold less potent to PI3K¦Á/¦Â/¦Ã, respectively.

prudect name : PIK-294 is a highly selective p110¦Ä inhibitor with IC50 of 10 nM, 1000-, 49- and 16-fold less potent to PI3K¦Á/¦Â/¦Ã, respectively.PIK-294 Synonyms: CAS NO: 900185-02-6Molecular Formula: C28H23N7O2Molecular…

📌

0💬 read more

Prasugrel is a novel platelet inhibitor used for the reduction of thrombotic cardiovascular events (including stent thrombosis) in patients with acute coronary syndrome who are to be managed with PCI

prudect name : Prasugrel is a novel platelet inhibitor used for the reduction of thrombotic cardiovascular events (including stent thrombosis) in patients with acute coronary syndrome who are to be…

📌

0💬 read more

Archive for June 2017