U-73343

Additional information:
U-73343, works as a protonophore, is an inactive analog of U-73122 and can be used as a negative control. U-73343 dose-dependently inhibits acid secretion irrespective of the stimulant. U-73122 is a phospholipase C (PLC) and 5-LO (5-lipoxygenase) inhibitor with an IC50 of 1-2.1 µM for PLC.|Product information|CAS Number: 142878-12-4|Molecular Weight: 466.66|Formula: C29H42N2O3|Chemical Name: 1-(6-[(1S,3aS,3bR,9bS,11aS)-7-methoxy-11a-methyl-1H,2H,3H,3aH,3bH,4H,5H,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-1-yl]aminohexyl)pyrrolidine-2,5-dione|Smiles: COC1C=C2CC[C@H]3[C@@H]4CC[C@H](NCCCCCCN5C(=O)CCC5=O)[C@@]4(C)CC[C@@H]3C2=CC=1|InChiKey: CJHWFIUASFBCKN-ZRJUGLEFSA-N|InChi: InChI=1S/C29H42N2O3/c1-29-16-15-23-22-10-8-21(34-2)19-20(22)7-9-24(23)25(29)11-12-26(29)30-17-5-3-4-6-18-31-27(32)13-14-28(31)33/h8,10,19,23-26,30H,3-7,9,11-18H2,1-2H3/t23-,24-,25+,26+,29+/m1/s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO : 5 mg/mL (10.Mupirocin Biological Activity 71 mM; Need ultrasonic).Ofatumumab In Vivo |Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.PMID:32891455 |Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|U73343, which potently inhibits acid secretion, shows no inhibitory effect on either K+-pNPPase or H+,K+-ATPase activity. U73343 dose-dependently inhibits, histamine (Hist)-, carbachol (CCh)-, and dbcAMPstimulated aminopyrine accumulation in gastric glands.|Products are for research use only. Not for human use.|