EPZ-6438 is a potent, selective, and orally bioavailable small-molecule inhibitor of EZH2 enzymatic activity with Ki value of 2.5¡À0.5 nM. IC50 Value: 2.5¡À0.5 nM (PRC2-containing wild-type EZH2)

June 21, 2017

prudect name : EPZ-6438 is a potent, selective, and orally bioavailable small-molecule inhibitor of EZH2 enzymatic activity with Ki value of 2.5¡À0.5 nM. IC50 Value: 2.5¡À0.5 nM (PRC2-containing wild-type EZH2)EPZ6438;…

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ENOblock(AP-III-a4) is a novel small molecule which is the first, nonsubstrate analogue that directly binds to enolase and inhibits its activity (IC50=0.576 uM); inhibit cancer cell metastasis in vivo.

prudect name : ENOblock(AP-III-a4) is a novel small molecule which is the first, nonsubstrate analogue that directly binds to enolase and inhibits its activity (IC50=0.576 uM); inhibit cancer cell metastasis…

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N-(Diaminomethylidene)-2-Methyl-5-Methylsulfonyl-4-Pyrrol-1-Ylbenzamide N-(Diaminomethylene)-2-Methyl-5-Methylsulfonyl-4-Pyrrol-1-Yl-Benzamide; N-(Diaminomethylene)-2-Methyl-5-Methylsulfonyl-4-(1-Pyrrolyl)Benzamide; N-(Diaminomethylene)-5-Mesyl-2-Methyl-4-Pyrrol-1-Yl-Benzamide

prudect name : N-(Diaminomethylidene)-2-Methyl-5-Methylsulfonyl-4-Pyrrol-1-Ylbenzamide N-(Diaminomethylene)-2-Methyl-5-Methylsulfonyl-4-Pyrrol-1-Yl-Benzamide; N-(Diaminomethylene)-2-Methyl-5-Methylsulfonyl-4-(1-Pyrrolyl)Benzamide; N-(Diaminomethylene)-5-Mesyl-2-Methyl-4-Pyrrol-1-Yl-BenzamideENIPORIDE Synonyms: CAS NO: 176644-21-6Molecular Formula: C14H16N4O3SMolecular Weight: 320.37Purity: 98% minSolubility: In DMSOStorage: −20°C 2 years CB 5083 References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18513700

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Etofenamate is a non-steroidal anti-inflammatory drug used for the treatment joint and muscular pain.

prudect name : Etofenamate is a non-steroidal anti-inflammatory drug used for the treatment joint and muscular pain.Etofenamate Synonyms: CAS NO: 30544-47-9Molecular Formula: C18H18F3NO4Molecular Weight: 369.33Purity: 98% minSolubility: in DMSOStorage: -20oC…

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prudect name : Eravacycline TP-434Synonyms: CAS NO: 1207283-85-9Molecular Formula: C27H31FN4O8Molecular Weight: 558.56Purity: 98% minSolubility: In

prudect name : Eravacycline TP-434 Synonyms: CAS NO: 1207283-85-9Molecular Formula: C27H31FN4O8Molecular Weight: 558.56Purity: 98% minSolubility: In DMSOStorage: −20°C 2 years JNJ 40411813 References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18513680

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prudect name : Ertapenem SodiumSynonyms: CAS NO: 153773-82-1Molecular Formula: C22H25N3O7S.NaMolecular Weight: 498.51Purity: 98% minSolubility: Storage:

prudect name : Ertapenem Sodium Synonyms: CAS NO: 153773-82-1Molecular Formula: C22H25N3O7S.NaMolecular Weight: 498.51Purity: 98% minSolubility: Storage: −20°C LCL 161 References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18513669

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EPZ015666 shows potent cellular activity that blocks symmetric dimethylation of SmD3 and inhibit proliferation of MCL cell lines (Z-138, Granta-519, Maver-1, Mino, and Jeko-1) with IC50 of 96-904 nM.EPZ015666 is a potent, selective and orally bioavailable PRMT5 inhibitor with Ki of 5 nM, >20,000-fold selectivity over other PMTs.

prudect name : EPZ015666 shows potent cellular activity that blocks symmetric dimethylation of SmD3 and inhibit proliferation of MCL cell lines (Z-138, Granta-519, Maver-1, Mino, and Jeko-1) with IC50 of…

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prudect name : Ezatiostat; Ter 199; Terrapin 199Synonyms: CAS NO: 168682-53-9Molecular Formula: C27H35N3O6SMolecular Weight: 529.65Purity:

prudect name : Ezatiostat; Ter 199; Terrapin 199 Synonyms: CAS NO: 168682-53-9Molecular Formula: C27H35N3O6SMolecular Weight: 529.65Purity: 98% minSolubility: in DMSOStorage: -20oC TGR1202 References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18513512

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ENMD-2076 tartrate has selective activity against Aurora A and Flt3 with IC50 of 14 nM and 1.86 nM, 25-fold selective for Aurora A than over Aurora B and less potent to VEGFR2/KDR and VEGFR3, FGFR1 and FGFR2 and PDGFR¦Á.

prudect name : ENMD-2076 tartrate has selective activity against Aurora A and Flt3 with IC50 of 14 nM and 1.86 nM, 25-fold selective for Aurora A than over Aurora B…

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prudect name : Erlotinib hydrochlorideSynonyms: CAS NO: 183319-69-9Molecular Formula: C22H23N3O4.HClMolecular Weight: 429.90Purity: 99%Solubility: In DMSOStorage:

prudect name : Erlotinib hydrochloride Synonyms: CAS NO: 183319-69-9Molecular Formula: C22H23N3O4.HClMolecular Weight: 429.90Purity: 99%Solubility: In DMSOStorage: −20°C 2 years PF04449913 References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18513424

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