prudect name : ethyl 6-chloronicotinateSynonyms: CAS NO: 49608-01-7Molecular Formula: C8H8ClNO2Molecular Weight: 185.61Purity: 98% minSolubility: Storage:

June 21, 2017

prudect name : ethyl 6-chloronicotinate Synonyms: CAS NO: 49608-01-7Molecular Formula: C8H8ClNO2Molecular Weight: 185.61Purity: 98% minSolubility: Storage: −20°C PD-0332991 References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18513392

📌

0💬 read more

For active viral replication, persistent elevations of serum transaminases ALT or liver histology showed chronic active lesions of adult hepatitis B treatment

prudect name : For active viral replication, persistent elevations of serum transaminases ALT or liver histology showed chronic active lesions of adult hepatitis B treatmentEntecavir hydrate Synonyms: CAS NO: 209216-23-9Molecular…

📌

0💬 read more

prudect name : ethyl 6-(pyrrolidin-1-yl)nicotinateSynonyms: CAS NO: 897399-74-5Molecular Formula: C12H16N2O2 Molecular Weight: 220.12 Purity: 98%

prudect name : ethyl 6-(pyrrolidin-1-yl)nicotinate Synonyms: CAS NO: 897399-74-5Molecular Formula: C12H16N2O2 Molecular Weight: 220.12 Purity: 98% minSolubility: Storage: −20°C CX5461 References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18513268

📌

0💬 read more

4-[(E)-1-[4-(2-Methylaminoethoxy)Phenyl]-2-Phenylbut-1-Enyl]Phenol 4-[(E)-1-[4-(2-Methylaminoethoxy)Phenyl]-2-Phenyl-But-1-Enyl]Phenol;

prudect name : 4-[(E)-1-[4-(2-Methylaminoethoxy)Phenyl]-2-Phenylbut-1-Enyl]Phenol 4-[(E)-1-[4-(2-Methylaminoethoxy)Phenyl]-2-Phenyl-But-1-Enyl]Phenol;Endoxifen Synonyms: CAS NO: 110025-28-0Molecular Formula: C25H27NO2Molecular Weight: 373.49Purity: 98% minSolubility: In DMSOStorage: −20°C 2 years LDN-193189 References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18513244

📌

0💬 read more

Eflornithine HCl acid can irreversibly inhibit ODC activity in the skin, the enzyme essential for the polyamine synthesis enzyme.

prudect name : Eflornithine HCl acid can irreversibly inhibit ODC activity in the skin, the enzyme essential for the polyamine synthesis enzyme.Eflornithine HCl Synonyms: CAS NO: 96020-91-6Molecular Formula: C6H12F2N2O2.HCl.H2OMolecular Weight:…

📌

0💬 read more

intermediates of Anidulafungin

prudect name : intermediates of AnidulafunginEchinocandin B Synonyms: CAS NO: 79411-15-7Molecular Formula: C34H51N7O15Molecular Weight: 797.81Purity: 70% minSolubility: In DMSOStorage: -20¡æ GDC 0853 References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18513211

📌

0💬 read more

Enzastaurin induced marked dose-dependent growth inhibition in all MM cell lines investigated including MM.1S, MM.1R, RPMI 8226 (RPMI), RPMI-Dox40 (Dox40), NCI-H929, KMS-11, OPM-2, and U266.IC50 ranged from 0.6 to 1.6 ¦ÌM. Enzastaurin has a direct effect on human tumor cells, inducing apoptosis and suppressing the proliferation of cultured tumor cells. Enzastaurin treatment also suppresses the phosphorylation of GSK3ßser9, ribosomal protein S6S240/244, and AKTThr308.

prudect name : Enzastaurin induced marked dose-dependent growth inhibition in all MM cell lines investigated including MM.1S, MM.1R, RPMI 8226 (RPMI), RPMI-Dox40 (Dox40), NCI-H929, KMS-11, OPM-2, and U266.IC50 ranged from…

📌

0💬 read more

Epothilone B (EPO906) is a new kind of cancer agents and microtubule function inhibitor with an IC50 of 3.5 nM. Epothilone B (EPO906) inhibits microtubule function. Microtubules are essential to cell division, and epothilones therefore stop cells from properly dividing. Epothilone B (EPO906) possesses the same biological effects as paclitaxel both in vitro and in cultured cells. epothilone B suppressed microtubule dynamics in a concentration-dependent manner coincident with mitotic block. At 0.2 nm epothilone B, dynamics were not significantly altered. At 2 nm epothilone B (EPO906) (IC33), the mean growth and shortening rates were decreased by 38 and 27%, respectively. Dynamicity was decreased by 47%. At the IC50, 80% of the cells had nearly complete stabilization of microtubule dynamics, and no anaphase or telophase figures were observed.

prudect name : Epothilone B (EPO906) is a new kind of cancer agents and microtubule function inhibitor with an IC50 of 3.5 nM. Epothilone B (EPO906) inhibits microtubule function. Microtubules…

📌

0💬 read more

Emtricitabine is a new nucleoside reverse transcriptase inhibitors.

prudect name : Emtricitabine is a new nucleoside reverse transcriptase inhibitors.Emtricitabine Synonyms: CAS NO: 143491-57-0Molecular Formula: C8H10FN3O3SMolecular Weight: 247.25Purity: ≥99%Solubility: Storage: −20°C 2 years GKT-137831 References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18512763

📌

0💬 read more

Epothilone D is a natural polyketide compound isolated from the myxobacterium Sorangium cellulosum. Also known as desoxyepothilone B, epothilone D binds to tubulin and inhibits the disassembly of microtubules, resulting in the inhibition of mitosis, cellular proliferation, and cell motility. Intermediary obtained in the synthesis of members of the Epothilone family, polyketide natural products that inhibit cancer cells via a mechanism similar to Paclitaxel. Epothilone D also found to be effective against Paclitaxel-resistant tumors. Epothilone D currently in Phase I of clinical testing.

prudect name : Epothilone D is a natural polyketide compound isolated from the myxobacterium Sorangium cellulosum. Also known as desoxyepothilone B, epothilone D binds to tubulin and inhibits the disassembly…

📌

0💬 read more

VD/VDR- vd-vdr

Posts by VD/VDR- vd-vdr