VD/VDR- vd-vdr

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Posts by VD/VDR- vd-vdr

DMXAA is a tumor-vascular disrupting agent with an IC50 of 9.46 ¡À 1.7 nM. It attacks the blood supply of a cancerous tumor to cause tumor regression. It has a striking antivascular and in some cases curative effect in experimental tumors. Its action on vascular endothelial cells seems to involve a cascade of events leading to induction of tumour haemorrhagic necrosis. These events include both direct and indirect effects, the latter involving the release of further vasoactive agents, such as serotonin, tumour necrosis factor, other cytokines, and nitric oxide from host cells.

 June 21, 2017

prudect name : DMXAA is a tumor-vascular disrupting agent with an IC50 of 9.46 ¡À 1.7 nM. It attacks the blood supply of a cancerous tumor to cause tumor regression….

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Daptomycin is a novel lipopeptide antibiotic used in the treatment of certain infections caused by Gram-positive organisms. It is a naturally-occurring compound found in the soil saprotroph Streptomyces roseosporus. Its distinct mechanism of action means that it may be useful in treating infections caused by multi-resistant bacteria.

prudect name : Daptomycin is a novel lipopeptide antibiotic used in the treatment of certain infections caused by Gram-positive organisms. It is a naturally-occurring compound found in the soil saprotroph…

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Dacinostat (NVP-LAQ824, LAQ824) is a highly potent HDAC inhibitor with IC50 of 32 nM,LAQ824 induces chromatin changes at the level of the IL-10 gene promoter that lead to enhanced recruitment of the transcriptional repressors HDAC11 and PU.1 and inhibits IL-10 production in BALB/c murine macrophages [

prudect name : Dacinostat (NVP-LAQ824, LAQ824) is a highly potent HDAC inhibitor with IC50 of 32 nM,LAQ824 induces chromatin changes at the level of the IL-10 gene promoter that lead…

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prudect name : Diphenylmethyl 7beta-Tert-Butoxycarbonylamino-3-Chloromethyl-3-Cephem-4-CarboxylateSynonyms: CAS NO: 112028-91-8Molecular Formula: C26H27ClN2O5SMolecular Weight: 515.02098Purity: 98% minSolubility: Storage:

prudect name : Diphenylmethyl 7beta-Tert-Butoxycarbonylamino-3-Chloromethyl-3-Cephem-4-Carboxylate Synonyms: CAS NO: 112028-91-8Molecular Formula: C26H27ClN2O5SMolecular Weight: 515.02098Purity: 98% minSolubility: Storage: −20°C BQ 788 sodium salt References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18511549

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trans-4-[4-(4-Amino-7,7-dimethyl-7H-pyrimido[4,5-b][1,4]oxazin-6-yl)phenyl]cyclohexaneacetic acid

prudect name : trans-4-[4-(4-Amino-7,7-dimethyl-7H-pyrimido[4,5-b][1,4]oxazin-6-yl)phenyl]cyclohexaneacetic acidDGAT-3 Synonyms: CAS NO: 701232-20-4Molecular Formula: C22H26N4O3Molecular Weight: 394.47Purity: 98% minSolubility: In DMSOStorage: -20°C LY-2606368 References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18511518

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Dronedarone hydrochloride for the treatment of arrhythmia.

prudect name : Dronedarone hydrochloride for the treatment of arrhythmia.Dronedarone hydrochloride Synonyms: CAS NO: 141625-93-6Molecular Formula: C31H44N2O5S.HClMolecular Weight: 593.22Purity: 99%Solubility: Storage: −20°C 2 years EPZ6438 References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18511498

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prudect name : DacarbazineSynonyms: CAS NO: 4342-03-4Molecular Formula: C6H10N6OMolecular Weight: 182.18Purity: 99%Solubility: Storage: −20°C

prudect name : Dacarbazine Synonyms: CAS NO: 4342-03-4Molecular Formula: C6H10N6OMolecular Weight: 182.18Purity: 99%Solubility: Storage: −20°C 2 years IPI 549 References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18511463

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Tetrandrine (Fanchinine; Hanfangchin A) is a calcium channel blocker with an IC50 of 38.23¡À 25.77 ¦ÌM. Tetrandrine (Fanchinine; Hanfangchin A) has anti-inflammatory, immunologic and antiallergenic effects. Tetrandrine (Fanchinine; Hanfangchin A) inhibits the degranulation of mast cells. Tetrandrinehas a “Quinidine like” anti-arrhythmic effect. Tetrandrine (Fanchinine; Hanfangchin A) has been isolated from Stephania tetandra and other Chinese and Japanese Herbs. Tetrandrine (Fanchinine; Hanfangchin A) increased populations of both apoptotic sub-G1 and G1 phase. Tetrandrine-induced growth inhibition was associated with induction of Cdk inhibitor p21, inhibition of cyclin D1 and activation of caspase-3. Tetrandrine (Fanchinine; Hanfangchin A) also affected the expression patterns of cytoskeletons including distribution of F-actin and expression level of microtubule.

prudect name : Tetrandrine (Fanchinine; Hanfangchin A) is a calcium channel blocker with an IC50 of 38.23¡À 25.77 ¦ÌM. Tetrandrine (Fanchinine; Hanfangchin A) has anti-inflammatory, immunologic and antiallergenic effects. Tetrandrine…

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prudect name : D-CloprostenolSynonyms: (+)-15(S)-CloprostenolCAS NO: 54276-22-1Molecular Formula: C22H29ClO6Molecular Weight: 424.9Purity: 98% minSolubility: Storage: -20¡æ

prudect name : D-Cloprostenol Synonyms: (+)-15(S)-CloprostenolCAS NO: 54276-22-1Molecular Formula: C22H29ClO6Molecular Weight: 424.9Purity: 98% minSolubility: Storage: -20¡æ ABT199 References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18511409

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(3S,8S,9S,12S)-3,12-Bis(1,1-dimethylethyl)-8-hydroxy-4,11-dioxo-9-(phenylmethyl)-2,5,6,10,13-pentaazatetradecanedioic acid 1,14-dimethyl ester

prudect name : (3S,8S,9S,12S)-3,12-Bis(1,1-dimethylethyl)-8-hydroxy-4,11-dioxo-9-(phenylmethyl)-2,5,6,10,13-pentaazatetradecanedioic acid 1,14-dimethyl esterDes(benzylpyridyl) Atazanavi Synonyms: CAS NO: 1192224-24-0Molecular Formula: C26H43N5O7Molecular Weight: 537.65Purity: 98% minSolubility: in DMSOStorage: -20oC LMI-070 References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18511348

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