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Posts by VD/VDR- vd-vdr

Basmisanil, also known as RG1662, RO5186582, is a highly selective inverse agonist/negative allosteric modulator of ¦Á5 subunit-containing GABAA receptors which is under development by Roche for the treatment of cognitive impairment associated with Down syndrome. As of August 2015, it is in phase II clinical trials for this indication. Down syndrome (DS) is the most commonly identifiable genetic form of intellectual disability. Individuals with DS have considerable deficits in intellectual functioning (i.e., low intellectual quotient, delayed learning and/or impaired language development) and adaptive behavior.

June 21, 2017

prudect name : Basmisanil, also known as RG1662, RO5186582, is a highly selective inverse agonist/negative allosteric modulator of ¦Á5 subunit-containing GABAA receptors which is under development by Roche for the…

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BAY 87-2243 is a highly potent and selective inhibitor of hypoxia-induced HIF-1 activation.

prudect name : BAY 87-2243 is a highly potent and selective inhibitor of hypoxia-induced HIF-1 activation.BAY 87-2243 Synonyms: CAS NO: 1227158-85-1Molecular Formula: C26H26F3N7O2Molecular Weight: 525.53Purity: 98% minSolubility: DMSOStorage: -20¡æ PF…

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Napabucasin is an orally-administered small molecule which can block cancer stem cell (CSC) self-renewal and induces cell death in CSCs as well as non-stem cancer cells.

prudect name : Napabucasin is an orally-administered small molecule which can block cancer stem cell (CSC) self-renewal and induces cell death in CSCs as well as non-stem cancer cells.BBI608£»Napabucasin Synonyms:…

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Bleomycin sulfate for the broad-spectrum antitumor antibiotic.

prudect name : Bleomycin sulfate for the broad-spectrum antitumor antibiotic.Bleomycin sulfate Synonyms: CAS NO: 9041-93-4Molecular Formula: C55H84N17O21S3.HSO4Molecular Weight: 1512.62Purity: 95%Solubility: Storage: −20°C 2 years NXL-104 References PubMed ID::http://www.ncbi.nlm.nih.gov/pubmed/18505681

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Emeramide, also known as BDTH2, a mercury chelator and an antioxidant, for the treatment of mercury poisoning. Phase I development is underway. BDTH2 is a colourless solid. The molecule consists of two thiol groups and linked via a pair of amide groups. BDTH2 can be used to chelate heavy metals like lead, cadmium, copper, manganese, zinc, iron, and mercury from ground water, coal tailings, gold ore, waste water of battery-recycling plants, and contaminated soil.

prudect name : Emeramide, also known as BDTH2, a mercury chelator and an antioxidant, for the treatment of mercury poisoning. Phase I development is underway. BDTH2 is a colourless solid….

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BMS-663068 is an HIV-1 attachment inhibitor in development for the treatment of HIV-1 infection.

prudect name : BMS-663068 is an HIV-1 attachment inhibitor in development for the treatment of HIV-1 infection.BMS663068 Fostemsavir Synonyms: CAS NO: 864953-29-7Molecular Formula: C25H26N7O8PMolecular Weight: 583.49Purity: 98% minSolubility: In DMSOStorage:…

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BRD4770 is a novel G9a(EHMT2) inhibitor with EC50 of 5 uM (trimethylated H3K9 in PANC-1 cell).

prudect name : BRD4770 is a novel G9a(EHMT2) inhibitor with EC50 of 5 uM (trimethylated H3K9 in PANC-1 cell).BRD4770 Synonyms: CAS NO: 1374601-40-7Molecular Formula: C25H23N3O3Molecular Weight: 413.47Purity: 98% minSolubility: DMSOStorage:…

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prudect name : Beraprost sodiumSynonyms: CAS NO: 88475-69-8Molecular Formula: C24H29NaO5Molecular Weight: 420.47Purity: 99%Solubility: Storage: -20¡æ

prudect name : Beraprost sodium Synonyms: CAS NO: 88475-69-8Molecular Formula: C24H29NaO5Molecular Weight: 420.47Purity: 99%Solubility: Storage: -20¡æ Apalutamide References PubMed ID::http://www.ncbi.nlm.nih.gov/pubmed/18505544

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(E)-5-(5-((3-(4-bromophenyl)-2-imino-4-oxothiazolidin-5-ylidene)methyl)furan-2-yl)isoindoline-1,3-dione

prudect name : (E)-5-(5-((3-(4-bromophenyl)-2-imino-4-oxothiazolidin-5-ylidene)methyl)furan-2-yl)isoindoline-1,3-dioneBioymifi Synonyms: CAS NO: 1420071-30-2Molecular Formula: C22H12BrN3O4SMolecular Weight: 493.0Purity: 98% minSolubility: in DMSOStorage: -20oC PA824 References PubMed ID::http://www.ncbi.nlm.nih.gov/pubmed/18505499

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Besifloxacin is a recently approved for the topical treatment of bacterial conjunctivitis fluoroquinolone drugs.

prudect name : Besifloxacin is a recently approved for the topical treatment of bacterial conjunctivitis fluoroquinolone drugs.Besifloxacin Synonyms: CAS NO: 141388-76-3Molecular Formula: C19H21ClFN3O3Molecular Weight: 393.84Purity: 99%Solubility: Storage: −20°C 2 years…

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