VD/VDR-vd-vdr.com

prudect name : Bimatoprost acidSynonyms: Bimatoprost acidCAS NO: 38344-08-0Molecular Formula: C23H32O5Molecular Weight: 388.5Purity: 99% minSolubility:

June 21, 2017

prudect name : Bimatoprost acid Synonyms: Bimatoprost acidCAS NO: 38344-08-0Molecular Formula: C23H32O5Molecular Weight: 388.5Purity: 99% minSolubility: Storage: −20°C 745-65-3 References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18503457

📌

0💬 read more

prudect name : beta-Methyl vinyl phosphateSynonyms: MAPCAS NO: 90776-59-3Molecular Formula: C29H27N2O10PMolecular Weight: 594.52Purity: 98% minSolubility:

prudect name : beta-Methyl vinyl phosphate Synonyms: MAPCAS NO: 90776-59-3Molecular Formula: C29H27N2O10PMolecular Weight: 594.52Purity: 98% minSolubility: Storage: −20°C 1247819-59-5 References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18503415

📌

0💬 read more

BX795 is a potent and specific PDK1 inhibitor with IC50 of 6 nM, 140- and 1600-fold more selective for PDK1 than PKA and PKC, respectively. Meanwhile, in comparison to GSK3¦Â more than 100-fold selectivity observed for PDK1.

prudect name : BX795 is a potent and specific PDK1 inhibitor with IC50 of 6 nM, 140- and 1600-fold more selective for PDK1 than PKA and PKC, respectively. Meanwhile, in…

📌

0💬 read more

BI 6727 is a highly potent Polo-like kinase inhibitor with an IC50 of 0 .87 nM BI 6727 has an EC50 of 11-37 nM on a panel of cancer cell lines and selective dihydropteridinone with distinct properties. BI 6727 has a pharmacokinetic profile favoring sustained exposure of tumor tissues with a high volume of distribution and a long terminal half-life in mice. BI 6727 has physicochemical and pharmacokinetic properties that allow in vivo testing of i.v. as well as oral formulations, adding flexibility to dosing schedules. BI 6727 shows marked antitumor activity in multiple cancer models, including a model of taxane-resistant colorectal cancer.

prudect name : BI 6727 is a highly potent Polo-like kinase inhibitor with an IC50 of 0 .87 nM BI 6727 has an EC50 of 11-37 nM on a panel…

📌

0💬 read more

BMS-599626 is a highly selective pan-HERKinase inhibitor with IC50 of 20 and 30 nM for the inhibition of HER1and HER2, respectively. HER1 expression has been shown in as much as 80% to 90% of colon and non¨Csmall- cell lung cancer. HER2 gene amplification and overexpression of the protein have been shown to occur in f30% of all breast cancer. BMS-599626 was highly selective when tested against a broad panel of diverse protein kinases. BMS-599626 abrogated HER1and HER2 signaling. BMS-599626 inhibited the proliferation of tumor cell lines that are dependent on these receptors, with IC50 in the range of 0.24 to 1 ¦ÌM.

prudect name : BMS-599626 is a highly selective pan-HERKinase inhibitor with IC50 of 20 and 30 nM for the inhibition of HER1and HER2, respectively. HER1 expression has been shown in…

📌

0💬 read more

BI 2536 is a small molecule compound with potential antineoplastic activities. BI 2536 binds to and inhibits Polo-like kinase 1 (Plk1, derived from human, mouse and rat) (with IC50of 0.83 nM), resulting in mitotic arrest, disruption of cytokinesis, and apoptosis in susceptible tumor cell populations.

prudect name : BI 2536 is a small molecule compound with potential antineoplastic activities. BI 2536 binds to and inhibits Polo-like kinase 1 (Plk1, derived from human, mouse and rat)…

📌

0💬 read more

prudect name : BoceprevirSynonyms: CAS NO: 394730-60-0Molecular Formula: C27H45N5O5Molecular Weight: 519.68Purity: 98% minSolubility: In DMSOStorage:

prudect name : Boceprevir Synonyms: CAS NO: 394730-60-0Molecular Formula: C27H45N5O5Molecular Weight: 519.68Purity: 98% minSolubility: In DMSOStorage: -20°C 191732-72-6 References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18503256

📌

0💬 read more

prudect name : beta-Estradiol semihydrateSynonyms: CAS NO: 35380-71-3Molecular Formula: 2(C18H24O2).H2OMolecular Weight: 562.79Purity: 98% minSolubility: Storage:

prudect name : beta-Estradiol semihydrate Synonyms: CAS NO: 35380-71-3Molecular Formula: 2(C18H24O2).H2OMolecular Weight: 562.79Purity: 98% minSolubility: Storage: −20°C 915019-65-7 References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18503218

📌

0💬 read more

BMS-708163 (Avagacestat) is a potent and selective ¦Ã-secretase inhibitor (GSI) (IC50 =0.3 nM).

prudect name : BMS-708163 (Avagacestat) is a potent and selective ¦Ã-secretase inhibitor (GSI) (IC50 =0.3 nM).BMS-708163 (Avagacestat) Synonyms: CAS NO: 1146699-66-2Molecular Formula: C20H17ClF4N4O4SMolecular Weight: 520.89Purity: 98% minSolubility: In DMSOStorage: −20°C…

📌

0💬 read more

Brivanib (BMS-540215) is hydrolyzed to the active moiety BMS-540215 in vivo. BMS-540215 shows potent and selective inhibition of VEGFR and FGFR tyrosine kinases . BMS-540215 is an ATP-competitive inhibitor of human VEGFR -2, with an IC50 of 25 nmol/L and Ki of 26 nmol/L. In addition, it inhibits VEGFR-1 (IC50 = 380 nmol/L) and VEGFR-3 (IC50 = 10 nmol/L). [1] BMS-540215 also showed good selectivity for FGFR-1 (IC50 = 148 nmol/L), FGFR-2 (IC50 =125 nmol/L), and FGFR-3 (IC50 = 68 nmol/L). Furthermore, BMS-540215 has been shown to selectively inhibit the proliferation of endothelial cells stimulated by VEGF and FGF in vitro with IC50 values of 40 and 276 nmol/L, respectively

prudect name : Brivanib (BMS-540215) is hydrolyzed to the active moiety BMS-540215 in vivo. BMS-540215 shows potent and selective inhibition of VEGFR and FGFR tyrosine kinases . BMS-540215 is an…

📌

0💬 read more