Zalcitabine is a nucleoside reverse transcriptase inhibitors

 June 21, 2017

prudect name : Zalcitabine is a nucleoside reverse transcriptase inhibitorsZalcitabine Synonyms: CAS NO: 7481-89-2Molecular Formula: 7481–89–2 Molecular Weight: 211.22Purity: 99% minSolubility: Storage: −20°C web site: www.medchemexpress.com

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(Z)-5-chloro-2-(2-(phenyl(pyridin-2-yl)methylene)hydrazinyl)pyridine

prudect name : (Z)-5-chloro-2-(2-(phenyl(pyridin-2-yl)methylene)hydrazinyl)pyridineZ-JIB-04 (NSC 693627) Synonyms: CAS NO: 199596-24-2Molecular Formula: C17H13ClN4Molecular Weight: 308.1Purity: 98% minSolubility: in DMSOStorage: -20oC web site: www.medchemexpress.com

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ZSTK474 inhibits class I PI3K isoforms with IC50 of 37 nM, mostly PI3K¦Ä.

prudect name : ZSTK474 inhibits class I PI3K isoforms with IC50 of 37 nM, mostly PI3K¦Ä.ZSTK 474 Synonyms: CAS NO: 475110-96-4Molecular Formula: C19H21F2N7O2Molecular Weight: 417.41Purity: 98% minSolubility: in DMSOStorage: -20oC…

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Z-VAD-FMK is a cell-permeable, irreversible pan-caspase inhibitor, blocks all features of apoptosis in THP.1 and Jurkat T-cells.Z-VAD-FMK (10 mM) inhibits apoptosis in THP.1 cells. Z-VAD-FMK (10 ¦ÌM) inhibits activation of PARP protease activity in control THP.1 cell lysates. Z-VAD-FMK (10 mM) inhibits the processing of CPP32 in intact THP.1 and Jurkat cells

prudect name : Z-VAD-FMK is a cell-permeable, irreversible pan-caspase inhibitor, blocks all features of apoptosis in THP.1 and Jurkat T-cells.Z-VAD-FMK (10 mM) inhibits apoptosis in THP.1 cells. Z-VAD-FMK (10 ¦ÌM)…

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Synonyms:4-(2-[7-AMINO-2-(2-FURYL)[1,2,4]TRIAZOLO[2,3-A][1,3,5]TRIAZIN-5-YLAMINO]ETHYL)PHENOL;ZM 241385;4-(2-(7-Amino-2-(furan-2-yl)-[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-ylamino)ethyl)phenol

prudect name : Synonyms:4-(2-[7-AMINO-2-(2-FURYL)[1,2,4]TRIAZOLO[2,3-A][1,3,5]TRIAZIN-5-YLAMINO]ETHYL)PHENOL;ZM 241385;4-(2-(7-Amino-2-(furan-2-yl)-[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-ylamino)ethyl)phenolZM 241385 Synonyms: CAS NO: 139180-30-6Molecular Formula: C16H15N7O2Molecular Weight: 337.34Purity: 98% minSolubility: In DMSOStorage: -20°C web site: www.medchemexpress.com

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A 179578; ABT 578; Resolute; 42-(1-Tetrazolyl)rapamycin; (42S)-42-Deoxy-42-(1H-tetrazol-1-yl)rapamycin

prudect name : A 179578; ABT 578; Resolute; 42-(1-Tetrazolyl)rapamycin; (42S)-42-Deoxy-42-(1H-tetrazol-1-yl)rapamycinZotarolimus A179578 ABT 578 Synonyms: CAS NO: 221877-54-9Molecular Formula: C52H79N5O12Molecular Weight: 966.21Purity: 98% minSolubility: In DMSOStorage: −20°C web site: www.medchemexpress.com

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ZM 336372 shows 10-fold selectivity over B-Raf. ZM 336372 weakly inhibits SAPK2a/p38¦Á and SAPK2b/p38¦Â with IC50 of 2 ¦ÌM, and is selective over 17 other protein kinases including PKA, PKC, AMPK, p42 MAPK, MKK1, SAPK1/JNK, and CDK1 even at the concentration of up to 50 ¦ÌM. ZM 336372 does not prevent constitutive as well as growth factor or phorbol ester induced activation of MKKl or p42 MAPK/ERK2. Moreover, ZM 336372 dose not reverse the phenotype of Ras- or Raf-transformed cell lines. ZM 336372 treatment induces >100 activation of c-Raf and the B-Raf isoform, but it does not trigger any activation of MKKI or p42 MAPK/ERKP or induce any increase in the GTP-loading of Ras, suggesting that a feedback control loop exists by which Raf isoforms suppress their own activation, such that inhibition is always counterbalanced by reactivation. ZM 336372-induced activation of c-Raf is not prevented by inhibition of the MAPK cascade, protein kinase C or phosphatidylinositide 3-kinase.

prudect name : ZM 336372 shows 10-fold selectivity over B-Raf. ZM 336372 weakly inhibits SAPK2a/p38¦Á and SAPK2b/p38¦Â with IC50 of 2 ¦ÌM, and is selective over 17 other protein kinases…

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Chemical Name: 4-[(4¡¯-Chloro-2¡¯-fluoro)phenylamino]-6,7-dimethoxyquinazoline hydrochloride

prudect name : Chemical Name: 4-[(4¡¯-Chloro-2¡¯-fluoro)phenylamino]-6,7-dimethoxyquinazoline hydrochlorideZM 306416 hydrochloride Synonyms: CAS NO: 690206-97-4Molecular Formula: C16H13N3O2FCl.HClMolecular Weight: 370.21Purity: 98% minSolubility: In DMSOStorage: −20°C web site: www.medchemexpress.com

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ZM 323881 HYDROCHLORIDE;5-((7-BENZYLOXYQUINAZOLIN-4-YL)AMINO)-4-FLUORO-2-METHYLPHENOL HYDROCHLORIDE

prudect name : ZM 323881 HYDROCHLORIDE;5-((7-BENZYLOXYQUINAZOLIN-4-YL)AMINO)-4-FLUORO-2-METHYLPHENOL HYDROCHLORIDEZM323881 Synonyms: CAS NO: 324077-30-7Molecular Formula: C22H19ClFN3O2Molecular Weight: 411.8565632Purity: 98% minSolubility: In DMSOStorage: −20°C web site: www.medchemexpress.com

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ZLN005 is a novel transcriptional regulator of peroxisome proliferator-activated receptor-¦Ã coactivator-1¦Á (PGC-1¦Á).

prudect name : ZLN005 is a novel transcriptional regulator of peroxisome proliferator-activated receptor-¦Ã coactivator-1¦Á (PGC-1¦Á).ZLN005 Synonyms: CAS NO: 49671-76-3Molecular Formula: C17H18N2Molecular Weight: 250.34Purity: 98% minSolubility: in DMSOStorage: -20oC web site:…

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