idarubicin is a semisynthetic 4-demethoxy analogue of the antineoplastic anthracycline antibiotic daunorubicin. Idarubicin intercalates into DNA and interferes with the activity of topoisomerase II, thereby inhibiting DNA replication, RNA transcription and protein synthesis. Due to its high lipophilicity, idarubicin penetrates cell membranes more efficiently than other anthracycline antibiotic compounds.

 June 21, 2017

prudect name : idarubicin is a semisynthetic 4-demethoxy analogue of the antineoplastic anthracycline antibiotic daunorubicin. Idarubicin intercalates into DNA and interferes with the activity of topoisomerase II, thereby inhibiting DNA…

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prudect name : IngenolSynonyms: CAS NO: 30220-46-3Molecular Formula: C20H26O5Molecular Weight: 346.42Purity: 98% minSolubility: in DMSOStorage:

prudect name : Ingenol Synonyms: CAS NO: 30220-46-3Molecular Formula: C20H26O5Molecular Weight: 346.42Purity: 98% minSolubility: in DMSOStorage: -20oC GSK1120212 References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18519656

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IKK¦Å-IN-1 is a potent IKK¦Å inhibitor; inhibit the in-situ ¦©K¦ª ¦Å-mediated phosphorylation of IRF3 with an IC50 value of less than about 100 nM.

prudect name : IKK¦Å-IN-1 is a potent IKK¦Å inhibitor; inhibit the in-situ ¦©K¦ª ¦Å-mediated phosphorylation of IRF3 with an IC50 value of less than about 100 nM.IKK¦Å-IN-1 Synonyms: CAS NO:…

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prudect name : Ivabradine hydrochlorideSynonyms: CAS NO: 148849-54-6Molecular Formula: C27H36N2O5.HClMolecular Weight: 505.05Purity: 99%Solubility: In DMSOStorage:

prudect name : Ivabradine hydrochloride Synonyms: CAS NO: 148849-54-6Molecular Formula: C27H36N2O5.HClMolecular Weight: 505.05Purity: 99%Solubility: In DMSOStorage: −20°C 2 years GM 6001 References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18519599

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Irinotecan is main use is in colon cancer, particularly in combination with other chemotherapy agents. The cytotoxicity of irinotecan and SN-38 in the two cell lines was as followed: irinotecan IC(50) values were 15.8 ¦ÌM for LoVo cells and 5.17 ¦ÌM for HT-29 cells; SN-38 IC(50) values were 8.25 nM for LoVo cells and 4.50 nM for HT-29 cells.

prudect name : Irinotecan is main use is in colon cancer, particularly in combination with other chemotherapy agents. The cytotoxicity of irinotecan and SN-38 in the two cell lines was…

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ITF2357 (Givinostat) is a potent inhibitor of HDAC with IC50 of 7.5-16 nM.

prudect name : ITF2357 (Givinostat) is a potent inhibitor of HDAC with IC50 of 7.5-16 nM.ITF2357 (Givinostat) Synonyms: CAS NO: 732302-99-7Molecular Formula: C24H27N3O4.HCl.H2OMolecular Weight: 475.97Purity: 98% minSolubility: In DMSOStorage: -20°C…

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INCB 3284 is a potent, selective and orally bioavailable hCCR2 antagonist with IC50 of 3.7 nM.

prudect name : INCB 3284 is a potent, selective and orally bioavailable hCCR2 antagonist with IC50 of 3.7 nM.INCB 3284 bimesylate Synonyms: CAS NO: 887401-93-6Molecular Formula: C26H31F3N4O4.2(CH4O3S)Molecular Weight: 624.60Purity: 98%…

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Synonyms:N-(3-Chloro-1H-indol-7-yl)-1,4-benzenedisulfonamide

prudect name : Synonyms:N-(3-Chloro-1H-indol-7-yl)-1,4-benzenedisulfonamideIndisulam Synonyms: CAS NO: 165668-41-7Molecular Formula: C14H12ClN3O4S2Molecular Weight: 385.85Purity: 98% minSolubility: in DMSOStorage: -20oC GG918 References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18519513

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IRAK inhibitor 6 is interleukin-1 receptor associated kinase 4 (IRAK-4) inhibitor

prudect name : IRAK inhibitor 6 is interleukin-1 receptor associated kinase 4 (IRAK-4) inhibitorIRAK inhibitor 6 Synonyms: CAS NO: 1042672-97-8Molecular Formula: C20H20N4O3SMolecular Weight: 396.46Purity: 98% minSolubility: In DMSOStorage: -20°C Pretomanid…

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prudect name : Ivabradine hydrochlorideSynonyms: CAS NO: 148849-67-6Molecular Formula: C27H36N2O5.HClMolecular Weight: 505.05Purity: 98% minSolubility: Storage:

prudect name : Ivabradine hydrochloride Synonyms: CAS NO: 148849-67-6Molecular Formula: C27H36N2O5.HClMolecular Weight: 505.05Purity: 98% minSolubility: Storage: -20°C I-BET762 References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18519489

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