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EMD534085 is a kinesin inhibitor currently in clinical development.

June 21, 2017

prudect name : EMD534085 is a kinesin inhibitor currently in clinical development.EMD 534085 Synonyms: CAS NO: 858668-07-2Molecular Formula: C25H31F3N4O2Molecular Weight: 476.53Purity: 98% minSolubility: In DMSOStorage: −20°C 2 years BIBF1120 References…

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Inhibitor of Wnt signaling. Induces an increase in Axin2 protein levels; promotes ¦Â-catenin phosphorylation by stabilizing Axin-scaffolded destruction complexes. Negative control exo-IWR (Cat. No. 3947) available.

prudect name : Inhibitor of Wnt signaling. Induces an increase in Axin2 protein levels; promotes ¦Â-catenin phosphorylation by stabilizing Axin-scaffolded destruction complexes. Negative control exo-IWR (Cat. No. 3947) available.endo-IWR 1…

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ETP-46464 is a cell-permeable quinoline-containing heterotricyclic compound that acts as a potent inhibitor against mTOR, ATR, DNA-PK, PI 3-K¦Á, and ATM (IC50= 0.6, 14, 36, 170, and 545 nM, respectively).

prudect name : ETP-46464 is a cell-permeable quinoline-containing heterotricyclic compound that acts as a potent inhibitor against mTOR, ATR, DNA-PK, PI 3-K¦Á, and ATM (IC50= 0.6, 14, 36, 170, and…

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lagolix is a highly potent, selective, orally-active, short-duration, non-peptide antagonist of the gonadotropin-releasing hormone receptor (GnRHR) (KD = 54 pM).

prudect name : lagolix is a highly potent, selective, orally-active, short-duration, non-peptide antagonist of the gonadotropin-releasing hormone receptor (GnRHR) (KD = 54 pM).Elagolix Synonyms: CAS NO: 834153-87-6Molecular Formula: C32H30F5N3O5Molecular Weight:…

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Enasidenib is a oral potent, selective, reversible inhibitor of mutant IDH2.

prudect name : Enasidenib is a oral potent, selective, reversible inhibitor of mutant IDH2.Enasidenib Synonyms: CAS NO: 1446502-11-9Molecular Formula: C19H17F6N7OMolecular Weight: 473.38Purity: 98% minSolubility: DMSOStorage: -20¡æ SU-5416 References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18511798

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prudect name : Exenatide acetateSynonyms: CAS NO: 141732-76-5Molecular Formula: C184H282N50O60S.C2H4O2Molecular Weight: 4262.67Purity: 98% minSolubility: Storage:

prudect name : Exenatide acetate Synonyms: CAS NO: 141732-76-5Molecular Formula: C184H282N50O60S.C2H4O2Molecular Weight: 4262.67Purity: 98% minSolubility: Storage: -20°C JNJ 28431754 References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18511765

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Enoxacin is a third generation fluoroquinolone antibiotic with broad-spectrum, potent bactericidal effect.

prudect name : Enoxacin is a third generation fluoroquinolone antibiotic with broad-spectrum, potent bactericidal effect.Enoxacin Synonyms: CAS NO: 74011-58-8Molecular Formula: C15H17FN4O3Molecular Weight: 320.32Purity: ≥99%Solubility: Storage: −20°C 2 years BKM120 References…

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Gefitinib(CAS NO:184475-35-2)Intermediates

prudect name : Gefitinib(CAS NO:184475-35-2)IntermediatesETHYL 2-AMINO-4,5-DIMETHOXYBENZOATE Synonyms: CAS NO: 20323-74-4Molecular Formula: C11H15NO4Molecular Weight: 225.24Purity: ≥98%Solubility: Storage: −20°C 2 years MK0974 References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18511753

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DY131, a selective ERR¦Ã agonist, could potentiate the ERR¦Ã-induced growth inhibition in LNCaP- ERR¦Ã and DU145- ERR¦Ã cells in a dose-dependent manner compared with respective parental cells. DY131 inhibited the growth of the ER¦Á-positive endometrial cancer cells but promoted that of the ER¦Á-negative cancer cells. DY131 had no effect on the structurally related receptors ERR¦Á or the estrogen receptors alpha and beta (ERalpha/beta). DY131 appears to inhibit Smo signaling through a common binding site shared by previously reported Smo agonists and antagonists.

prudect name : DY131, a selective ERR¦Ã agonist, could potentiate the ERR¦Ã-induced growth inhibition in LNCaP- ERR¦Ã and DU145- ERR¦Ã cells in a dose-dependent manner compared with respective parental cells….

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Dimethyloxallyl Glycine(DMOG) is a cell permeable, competitive inhibitor of HIF-PH(HIF-1¦Á prolyl hydroxylase).

prudect name : Dimethyloxallyl Glycine(DMOG) is a cell permeable, competitive inhibitor of HIF-PH(HIF-1¦Á prolyl hydroxylase).Dimethyloxaloylglycine (DMOG) Synonyms: CAS NO: 89464-63-1Molecular Formula: C6H9NO5Molecular Weight: 175.14Purity: 98% minSolubility: Storage: -20oC FG4592 References…

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