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prudect name : CamptothecinSynonyms: CAS NO: 7689-3-4Molecular Formula: C20H16N2O4Molecular Weight: 348.36Purity: ≥99%Solubility: Storage: −20°C

June 21, 2017

prudect name : Camptothecin Synonyms: CAS NO: 7689-3-4Molecular Formula: C20H16N2O4Molecular Weight: 348.36Purity: ≥99%Solubility: Storage: −20°C 2 years BIBW-2992 References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18508405

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CW-069 is a novel and allosteric inhibitor of the microtubule motor protein HSET with IC50 value of 75 ¡À 20 ¦ÌM; shows statistically significant selectivity over KSP.

prudect name : CW-069 is a novel and allosteric inhibitor of the microtubule motor protein HSET with IC50 value of 75 ¡À 20 ¦ÌM; shows statistically significant selectivity over KSP.CW069;CW-069…

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CUDC-907 is an orally bioavailable inhibitor of both phosphoinositide 3-kinase (PI3K) class I and pan histone deacetylase (HDAC) enzymes, with potential antineoplastic activity. Upon oral administration, CUDC-907 inhibits the activity of both PI3K class I isoforms and HDAC, thereby preventing the activation of the PI3K-AKT-mTOR signal transduction pathway that is often overactivated in many cancer cell types. This may prevent growth of PI3K and/or HDAC-expressing tumor cells. CUDC-907 shows an increased inhibition of tumor cell growth and induction of apoptosis when compared to inhibitors that target either PI3K or HDAC. Check for active clinical trials or closed clinical trials using this agent.

prudect name : CUDC-907 is an orally bioavailable inhibitor of both phosphoinositide 3-kinase (PI3K) class I and pan histone deacetylase (HDAC) enzymes, with potential antineoplastic activity. Upon oral administration, CUDC-907…

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prudect name : CabazitaxelSynonyms: CAS NO: 183133-96-2Molecular Formula: C45H57NO14Molecular Weight: 835.93Purity: 98% minSolubility: In DMSOStorage:

prudect name : Cabazitaxel Synonyms: CAS NO: 183133-96-2Molecular Formula: C45H57NO14Molecular Weight: 835.93Purity: 98% minSolubility: In DMSOStorage: -20°C AT-9283 References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18508352

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prudect name : Cabazitaxel N-1Synonyms: CAS NO: 1354900-66-5Molecular Formula: C47H59NO15Molecular Weight: Purity: 98% minSolubility: In

prudect name : Cabazitaxel N-1 Synonyms: CAS NO: 1354900-66-5Molecular Formula: C47H59NO15Molecular Weight: Purity: 98% minSolubility: In DMSOStorage: -20°C JIB04 References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18508252

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CCT244747 is a novel potent, highly selective, orally active ATP-competitive CHK1 inhibitor with potential anticancer activity. CCT244747 inhibited cellular CHK1 activity (IC(50) 29-170 nmol/L), significantly enhanced the cytotoxicity of several anticancer drugs, and abrogated drug-induced S and G(2) arrest in multiple tumor cell lines. CCT244747 represents the first structural disclosure of a highly selective, orally active CHK1 inhibitor and warrants further evaluation alone or combined with genotoxic anticancer therapies.

prudect name : CCT244747 is a novel potent, highly selective, orally active ATP-competitive CHK1 inhibitor with potential anticancer activity. CCT244747 inhibited cellular CHK1 activity (IC(50) 29-170 nmol/L), significantly enhanced the…

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Cerdulatinib(PRT-062070; PRT2070) is an novel oral dual Syk/JAK inhibitor.

prudect name : Cerdulatinib(PRT-062070; PRT2070) is an novel oral dual Syk/JAK inhibitor.Cerdulatinib (PRT062070, PRT2070) Synonyms: CAS NO: 1198300-79-6Molecular Formula: C20H27N7O3SMolecular Weight: 445.54Purity: 98% minSolubility: In DMSOStorage: -20 oC NND 502…

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Prasugrel(CAS NO:150322-43-3)intermediates

prudect name : Prasugrel(CAS NO:150322-43-3)intermediatesCyclopropyl 2-fluorobenzyl ketone Synonyms: CAS NO: 150322-73-9Molecular Formula: C11H11FOMolecular Weight: 178.20Purity: ≥98%Solubility: Storage: −20°C 2 years SP-2509 References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/1850821

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Prasugrel(CAS NO:150322-43-3)intermediates

prudect name : Prasugrel(CAS NO:150322-43-3)intermediatesCylopropylcarbonyl-2-flurobenzyl bromide Synonyms: CAS NO: 204205-33-4Molecular Formula: C11H10BrFOMolecular Weight: 257.10Purity: ≥98%Solubility: Storage: −20°C 2 years AP23573 References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18508209

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CPI203 inhibits BRD4 in vitro and in cells, while does not affect BRD4 kinase activity in vitro.CPI203 exerts a cytostatic effect in all the 9 MCL cell lines analyzed with GI50 ranging from 0.06 to 0.71 ¦ÌM, with low cytotoxicity in normal PBMCs from healthy donors. Furthermore, lenalidomide and CPI203, by targeting IRF4 and MYC, efficiently activates the cell death program in MCL cells resistant to bortezomib

prudect name : CPI203 inhibits BRD4 in vitro and in cells, while does not affect BRD4 kinase activity in vitro.CPI203 exerts a cytostatic effect in all the 9 MCL cell…

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