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BIX 02189 is a selective MEK5/ERK5 inhibitor with an IC50 of 59 nM. It inhibited catalytic function of purified, MEK5 enzyme. The MEK5 inhibitors blocked phosphorylation of ERK5, without affecting phosphorylation of ERK1/2 in sorbitol-stimulated HeLa cells. The compounds also inhibited transcriptional activation of MEF2C, a downstream substrate of the MEK5/ERK5 signaling cascade, in a cellular trans-reporter assay system.

June 21, 2017

prudect name : BIX 02189 is a selective MEK5/ERK5 inhibitor with an IC50 of 59 nM. It inhibited catalytic function of purified, MEK5 enzyme. The MEK5 inhibitors blocked phosphorylation of…

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Bortezomib is the 26S proteasome in mammalian cells and reversible inhibitor of chymotrypsin-like activity, treatment of relapsed or refractory advanced non-small cell lung cancer (NSCLC) and effective.

prudect name : Bortezomib is the 26S proteasome in mammalian cells and reversible inhibitor of chymotrypsin-like activity, treatment of relapsed or refractory advanced non-small cell lung cancer (NSCLC) and effective.Bortezomib…

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prudect name : BMH-21Synonyms: CAS NO: 896705-16-1Molecular Formula: C21H20N4O2Molecular Weight: 360.41Purity: 98% minSolubility: in DMSOStorage:

prudect name : BMH-21 Synonyms: CAS NO: 896705-16-1Molecular Formula: C21H20N4O2Molecular Weight: 360.41Purity: 98% minSolubility: in DMSOStorage: -20oC NLG-919 References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18504431

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prudect name : Boc-L-ValineSynonyms: CAS NO: 13734-41-3Molecular Formula: C10H19NO4Molecular Weight: 217.26Purity: 98%Solubility: Storage: −20°C

prudect name : Boc-L-Valine Synonyms: CAS NO: 13734-41-3Molecular Formula: C10H19NO4Molecular Weight: 217.26Purity: 98%Solubility: Storage: −20°C 2 years Eph receptor tyrosine kinase inhibitor References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18504422

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BIO-acetoxime is a potent dual GSK3¦Á/¦Â inhibitor with IC50 of 10 nM, >240-fold selectivity over CDK5/p25, CDK2/cyclin A and CDK1/cyclin B.

prudect name : BIO-acetoxime is a potent dual GSK3¦Á/¦Â inhibitor with IC50 of 10 nM, >240-fold selectivity over CDK5/p25, CDK2/cyclin A and CDK1/cyclin B.BIO-acetoxime Synonyms: CAS NO: 667463-85-6Molecular Formula: C18H12BrN3O3Molecular…

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BIBR 1532 is a potent, selective, non-competitive telomerase inhibitor with IC50 of 100 nM in a cell-free assay.

prudect name : BIBR 1532 is a potent, selective, non-competitive telomerase inhibitor with IC50 of 100 nM in a cell-free assay.BIBR 1532 Synonyms: CAS NO: 321674-73-1Molecular Formula: C21H17NO3Molecular Weight: 331.36Purity:…

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prudect name : Brivudine;BromovinyldeoxyuridineSynonyms: CAS NO: 69304-47-8Molecular Formula: C11H13BrN2O5Molecular Weight: 333.14Purity: 98% minSolubility: in DMSOStorage:

prudect name : Brivudine;Bromovinyldeoxyuridine Synonyms: CAS NO: 69304-47-8Molecular Formula: C11H13BrN2O5Molecular Weight: 333.14Purity: 98% minSolubility: in DMSOStorage: -20oC SB1518 References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18504338

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prudect name : BCzVBiSynonyms: BCzVBiCAS NO: 158604-97-8Molecular Formula: C44H36N2Molecular Weight: Purity: Solubility: Storage:

prudect name : BCzVBi Synonyms: BCzVBiCAS NO: 158604-97-8Molecular Formula: C44H36N2Molecular Weight: Purity: Solubility: Storage: ML-265 References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18504331

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prudect name : BMS-946815Synonyms: BMS946815CAS NO: 244154-66-3Molecular Formula: C24H30CIN3O4Molecular Weight: 459.19Purity: 98% minSolubility: In DMSOStorage:

prudect name : BMS-946815 Synonyms: BMS946815CAS NO: 244154-66-3Molecular Formula: C24H30CIN3O4Molecular Weight: 459.19Purity: 98% minSolubility: In DMSOStorage: −20°C AZD-1775 References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18504307

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prudect name : Bicyclo[2.2.2]Octane-1,4-Dicarboxylic AcidSynonyms: CAS NO: 711-02-4Molecular Formula: C10H14O4Molecular Weight: 198.2158Purity: 98% minSolubility: Storage:

prudect name : Bicyclo[2.2.2]Octane-1,4-Dicarboxylic Acid Synonyms: CAS NO: 711-02-4Molecular Formula: C10H14O4Molecular Weight: 198.2158Purity: 98% minSolubility: Storage: −20°C Pevonedistat References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18504295

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