prudect name : HexarelinSynonyms: CAS NO: 140703-51-1Molecular Formula: C47H58N12O6Molecular Weight: 887.04Purity: 98% minSolubility: Storage: -20°C

June 21, 2017

prudect name : Hexarelin Synonyms: CAS NO: 140703-51-1Molecular Formula: C47H58N12O6Molecular Weight: 887.04Purity: 98% minSolubility: Storage: -20°C VX 765 References PubMed ID๏ผš:http://www.ncbi.nlm.nih.gov/pubmed/18518906

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HPGDS inhibitor 1 is a novel and selective Hematopoietic Prostaglandin D Synthase (HPGDS) inhibitor with an IC50 Value of 0.7 nM.

prudect name : HPGDS inhibitor 1 is a novel and selective Hematopoietic Prostaglandin D Synthase (HPGDS) inhibitor with an IC50 Value of 0.7 nM.HPGDS inhibitor-1 Synonyms: CAS NO: 1033836-12-2Molecular Formula:…

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Biological Activity:Cell-permeable inhibitor of Bcl-2 protein (IC50 ~ 9 ยฆรŒM); acts by binding to the surface pocket. Disrupts Bax/Bcl-2 interaction and induces apoptosis of tumor cells. Also binds to the antiapoptotic Blc-2 proteins Bcl-XL and Bcl-w.

prudect name : Biological Activity:Cell-permeable inhibitor of Bcl-2 protein (IC50 ~ 9 ยฆรŒM); acts by binding to the surface pocket. Disrupts Bax/Bcl-2 interaction and induces apoptosis of tumor cells. Also…

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GSK-LSD1 2HCl is an irreversible, and selective LSD1 inhibitor with IC50 of 16 nM, > 1000 fold selective over other closely related FAD utilizing enzymes (i.e. LSD2, MAO-A, MAO-B).

prudect name : GSK-LSD1 2HCl is an irreversible, and selective LSD1 inhibitor with IC50 of 16 nM, > 1000 fold selective over other closely related FAD utilizing enzymes (i.e. LSD2,…

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GDC-0994 is a potent, orally available ERK1/2 inhibitor with IC50 of 1.1 nM and 0.3 nM, respectively.

prudect name : GDC-0994 is a potent, orally available ERK1/2 inhibitor with IC50 of 1.1 nM and 0.3 nM, respectively.GDC-0994 Synonyms: CAS NO: 1453848-26-4Molecular Formula: C21H18ClFN6O2Molecular Weight: 440.86Purity: 98% minSolubility:…

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VGX-1027(GIT27) is an isoxazole compound that exhibits various immunomodulatory properties; reduce the secretion of IL-1beta, TNF-alpha and IL-10 from purified murine macrophages.

prudect name : VGX-1027(GIT27) is an isoxazole compound that exhibits various immunomodulatory properties; reduce the secretion of IL-1beta, TNF-alpha and IL-10 from purified murine macrophages.GIT 27; VGX 1027 Synonyms: CAS…

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Biological Activity Potent pan-Trk inhibitor. Displays antiproliferative effects in cellular Ba/F3 assays (IC50 values are 7, 9 and 11 nM for cells containing the fusion proteins Tel-TrkC, Tel-TrkB and Tel-TrkA, respectively). Exhibits selectivity for Trk receptors over a range of kinases, with some activity at PDGFR and c-Kit (IC50 values are 0.87 and 0.91 ยฆรŒM respectively). Orally bioavailable.

prudect name : Biological Activity Potent pan-Trk inhibitor. Displays antiproliferative effects in cellular Ba/F3 assays (IC50 values are 7, 9 and 11 nM for cells containing the fusion proteins Tel-TrkC,…

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5-(2-Fluoro-4-iodophenylamino)imidazo[1,5-a]pyridine-6-carboxylic acid N-(2-hydroxyethoxy)amide; RG 7421

prudect name : 5-(2-Fluoro-4-iodophenylamino)imidazo[1,5-a]pyridine-6-carboxylic acid N-(2-hydroxyethoxy)amide; RG 7421GDC 0623 Synonyms: GDC-0623CAS NO: 1168091-68-6Molecular Formula: C16H14FIN4O3Molecular Weight: 456.21Purity: 98% minSolubility: in DMSOStorage: -20oC BGB324 References PubMed ID๏ผš:http://www.ncbi.nlm.nih.gov/pubmed/1851822

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GLPG0634(filgotinib) is a selective JAK1 inhibitor with IC50 of 10 nM, 28 nM, 810 nM, and 116 nM for JAK1, JAK2, JAK3, and TYK2, respectively

prudect name : GLPG0634(filgotinib) is a selective JAK1 inhibitor with IC50 of 10 nM, 28 nM, 810 nM, and 116 nM for JAK1, JAK2, JAK3, and TYK2, respectivelyGLPG0634(filgotinib) Synonyms: CAS…

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GW-6604;2-Phenyl-4-[3-(pyridin-2-yl)-1H-pyrazol-4-yl]pyridine

prudect name : GW-6604;2-Phenyl-4-[3-(pyridin-2-yl)-1H-pyrazol-4-yl]pyridineGW-6604 Synonyms: CAS NO: 452342-37-9Molecular Formula: C19H14N4Molecular Weight: 298.34126Purity: 98% minSolubility: in DMSOStorage: -20oC RG-7388 References PubMed ID๏ผš:http://www.ncbi.nlm.nih.gov/pubmed/18517923

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