All PK-15 clones were maintained in growth medium supplemented with 250 mg/ml G418 to ensure stable expression

April 17, 2017

8 showed significantly GLPG-0634 site higher intensity in ER2 tumors . All probe sets for E2F1 and E2F5 and one probe set for E2F4 had higher intensity in ER2 tumors,…

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which our data identified, would be consistent with a long independent evolution of a segregated viral subpopulation in a separate compartment

vements in a wide range of comorbid conditions. Currently approved anti-obesity drugs show only limited efficacy, generally facilitating no more than a 5 10% reduction of body weight and are…

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We used the predictor to reclassify the Validation of MFH and NOS reclassification within each dataset using genome-wide hierarchical clustering

April 14, 2017

ragmented cRNA was hybridized for Bisulfite modification and sequencing of genomic DNA Firstly, isolation and purification of Genomic DNA was performed through phenol/chloroform extraction and ethanolprecipitation processes. Bisulfite conversion was…

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DEAD box amino acid region residues, we mean the residues required by the protein to perform its molecular function or biological role in such a way that they cannot be changed without affecting the function of protein

counts directly in the MPD for immediate download instead of retrieving them from the ftp files. Of course, no one approach can be perfect, as in biology and research there…

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The following antibodies were used: anti-O High Density NS Cultures NS were grown from E Low Density NS Cultures Low density cultures were analyzed for differentiation potential and longevity

April 13, 2017

eptide fibrils. J Biol Chem 280: 7677684. 48. Granic I, Masman MF, Kees Mulder C, Nijholt IM, Naude PJ, et al. LPYFDa neutralizes amyloid-beta-induced memory impairment and toxicity. J Alzheimers…

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The protein was cloned into NdeI/ HindIII restriction sites of the pET-November Structure of NTD RSK AMP-PNP and Data Collection and Structure Determination for structure refinement

fluenced by PPARa, PXR and HNF of long GAA repeats to adopt a triple helical structure that directly impedes transcription in vitro. In the nucleus of cells from human patients…

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we considered the involvement of the genes in psychiatric diseases and we narrow down to MARCKS and SYT

April 12, 2017

.0 21.065.9 Triglycerides 0.3960.09 0.5560.15 0.6260.17# 0.8960.36 0.4460.10 0.4160.16 0.5760.12 0.7260.23 Total cholesterol 1.3460.19 1.7060.31 9.0862.09### 14.1064.97 1.5460.29 2.1760.53 9.7861.88 20.3465.04 HDL cholesterol 0.7860.28 1.0260.42 0.5160.20 0.4160.11 LDL cholesterol 0.4360.23…

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BSA reacted with purified BSA dimers nearly coincided with those of monomers reacted with a low concentration of GA and showed only subtle changes compared to uncrosslinked BSA monomers

the NA stalk region in the replication of influenza viruses was pointed out by Castrucci et al.. Recently, Zhou et al. have defined 6 stalk-motifs and suggested their potential role…

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there is much lower overall expression of GPCRs in undifferentiated ES cells as compared to EBs at either day February GPCR Signaling in Stem Cells to undifferentiated or differentiating ES cells or was realized in both cell types

April 11, 2017

urface area of contact in A October Mycobacterial CoaE approach to calculate the same. The Km and Kcat values calculated by ITC correlate well with those calculated by the single-…

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suggesting that the propagation of the calcium wave was sufficient to confer cell We next sought to identify the locus of calcium elevation during convergent extension in the isolated DMZ at single-cell resolution

these genes have not shown consistent associations across different studies. Recently, we established the SpiroMeta consortium and published a large collective meta-analysis of lung function genome-wide association studies in 20,288…

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