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mitochondrial membranes seen by EM. This may explain our observations of altered mitochondrial morphology in PINK1 deficient human neurons. The importance of glutathione in recessive PD has already been explored:…

lines 102 pediatric AML patient samples were 14937-32-7 obtained at the time of diagnosis after informed consent from the Oncogenetic laboratory of the Pediatric Oncology and Hematology department of the…

s surrounding exon 7, which codes for amino acids 134185 of the PME-1 gene. The 59 and 39 homologous recombination fragments were subcloned into the NotI and BamHI sites and…

or a possible role of androgens in trout skeletal muscle function as inferred from the identification of the androgen receptor as well as from genes that increase AR expression, such…

ding to an overall ��null��effect. Most of the identified miRNAs exhibited changes in one disease state rather than showing a quantitative trend of increasing or decreasing expression paralleling the severity…

searches were performed against the SwissProt database to which was added the T. brucei subset of the TriTrypDB database v. 4.1 totaling 563,498 entries. For estimation of false discovery rates,…

d with a retroviral vector expressing C/EBPa. To define whether overexpression of C/ EBPa could rescue adipogenesis in FUS-DDIT3 cells, adipocytic differentiation was induced in FUS-DDIT3 MEFs infected either with…

tion reduction, phospholipid catabolism Protein name Glial fibrillary acidic protein isoform 1 Up/down regulation qQQQQ QQQQQ Accession number Cellular localization P14136 Cytoplasm, intermedier filament Molecular function Central nervous system development,…

olymerase was used for PCR. The primers specific to pig APOBEC3F were 59-TGG TCA CAG AGC TGA AGC AG and 59-TTG TTT TGG AAG CAG CCT TT. The semi-nested primer…

revealed that the local chromatin organization is one of the major players in the in vivo regulation of globin genes expression. There are 5 developmentally specific genes including embryonic, fetal,…